Every once and awhile when using SOIC (Storage IO Control) within ESXi the hosts will get out of wack with regards to reading and writing to the slotsfile. If you take a look at your syslog output you might see something like the below. 2013-12-12T06:49:58.987Z vmsrv-13.uwgb.edu storageRM: open /vmfs/volumes//VM-LUN-1/.naa.60002ac0000000000000002900001234/slotsfile(0x10000042, 0x0) failed: No such file or …